CARD14 anticorps (C-Term)

N° du produit ABIN6990437

L’anticorps Lapin Polyclonal anti-CARD14 a été validé pour ELISA et IHC (p). Il convient pour détecter CARD14 dans des échantillons de Humain.

Aperçu rapide pour CARD14 anticorps (C-Term) (ABIN6990437)

Antigène: CARD14 (Caspase Recruitment Domain Family, Member 14 (CARD14))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CARD14 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CARD14 anticorps

Épitope: C-Term

Specificité: CARMA2 antibody is human specific. At least three isoforms of CARMA2 are known to exist, this antibody will only detect isoform 1. CARMA2 antibody is predicted not to cross-react with other CARMA proteins.

Purification: CARMA2 Antibody is affinity chromatography purified via peptide column.

Immunogène: CARMA2 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human CARMA2. The immunogen is located within the last 50 amino acids of CARMA2.

Isotype: IgG

Information d'application

Indications d'application: CARMA2 antibody can be used for detection of CARMA2 by immunohistochemistry at 5 μ,g/mL.

Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: CARMA2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: CARMA2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CARD14

Antigène: CARD14 (Caspase Recruitment Domain Family, Member 14 (CARD14))

Autre désignation: CARMA2

Sujet: CARMA2 Antibody: CARMA proteins belong to the membrane-associated guan-ylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules. CARMA1, CARMA2, and CARMA3 share high degrees of sequence and functional homology, but their tissue-specific distribution suggests that they serve distinct biological functions in different cell types. As with CARMA1, the CARD domain of CARMA2 has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-κ,B activation. When expressed in cells, this protein activated NF-κ,B and induced the phosphorylation of BCL10 Alternative splicing of CARMA2 results in isoforms that possess differential effects on NF-κ,B activation and endoplasmic reticulum stress-induced cell death.

ID gène: 79092

NCBI Accession: NP_077015

UniProt: Q9BXL6